Volume 37 (4), September 2022 | Page 42

• Vomiting / nausea
• Hypersalivation
Gastrointestinal
Cardiovascular
• Dramatic changes in blood pressure
• Tachycardia
• Arrhythmia
• Venous distension
• Cyanotic MM – TACO / TRALI
• Brick-red MM – anaphylaxis
• Haemoglobulinuria
• Fever
Other
Transfusion reaction
Common clinical signs
Respiratory
• Tachypnoea
• Increased respiratory effort
• Care with small dogs and those suffering from renal or cardiac disease – increased risk of TACO
• Erythema
• Hives
Dermatological
Neurological
• Mentation / behavioural changes
• Citrate toxicity = hypocalcaemia = tremors , facial rubbing , seizures
Figure 1 . Transfusion reaction – common clinical signs . MM , Mucous membranes ; TACO , transfusion-associated circulatory overload ; TRALI , transfusion-related acute lung injury .
Table 3 . Potential causes of anaemia ( Mills , 2000 ). RBC , Red blood cell .
Increased RBC loss Increased RBC destruction ( haemolysis ) Decreased production of RBCs
• Acute / chronic haemorrhage • Immune-mediated haemolytic anaemia
• Pyruvate kinase deficiency
• Onion ingestion
• Zinc toxicosis
• Snake bite
• Disseminated intravascular coagulopathy ( DIC )
• Metastatic tumour
• Heartworm
• Nutritional deficiencies
• Drugs ( e . g . some cytotoxic drugs )
• Chronic disease
• Leukaemia
• Multiple myeloma
• Renal disease
• Hepatopathies
• Endocrine disease
• Babesiosis
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