VNJ Volume 41 (4) August 2026 | Page 27

Plus-Hex CLINICAL
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20 Korpivaara M, Laapas K, Huhtinen M, Schöning B, Overall K. Dexmedetomidine oromucosal gel for noise-associated acute anxiety and fear in dogs— a randomised, double-blind, placebo-controlled clinical study. Veterinary Record. 2017; 180( 14): 356. Available from: https:// doi. org / 10.1136 / vr. 104045.
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30 Höglund K, Hanås S, Carnabuci C, Ljungvall I, Tidholm A, Häggström J. Blood pressure, heart rate, and urinary catecholamines in healthy dogs subjected to different clinical settings. Journal of Veterinary Internal Medicine. 2012; 26( 6): 1300 – 1308. Available from: https:// doi. org / 10.1111 / j. 1939-1676.2012.00999. x.
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32 Gruen M, Case BC, Robertson JB, Campbell S, Korpivaara ME. Evaluation of repeated dosing of a dexmedetomidine oromucosal gel for treatment of noise aversion in dogs over a series of noise events. Veterinary Record. 2020; 187( 12): 489. Available from: https:// doi. org / 10.1136 / vr. 106046.
33 Piotti P, Uccheddu S, Alliani M, Mariti C, Nuti V, Ogi A, et al. Management of specific fears and anxiety in the behavioural medicine of companion animals: punctual use of psychoactive medications. Dog Behavior. 2019; 5( 2): 23 – 30. Available from: https:// doi. org / 10.4454 / db. v5i2.109.
34 Mills DS, Demontigny-Bédard I, Gruen M, Klinck MP, McPeake KJ, Barcelos AM, et al. Pain and problem behavior in cats and dogs. Animals. 2020; 10( 2): 318. Available from: https:// doi. org / 10.3390 / ani10020318.
35 Messenger KM, Hopfensperger M, Knych HK, Papich MG. Pharmacokinetics of detomidine following intravenous or oraltransmucosal administration and sedative effects of the oraltransmucosal treatment in dogs. American Journal of Veterinary Research. 2016; 77( 4): 413 – 420. Available from: https:// doi. org / 10.2460 / ajvr. 77.4.413.
36 Hopfensperger M, Messenger K, Papich M, Sherman B. The use of oral transmucosal detomidine hydrochloride gel to facilitate handling in dogs. Journal of Veterinary Behavior. 2013; 8( 3): 114 – 123. Available from: https:// doi. org / 10.1016 / j. jveb. 2012.10.004.
37 Ogata N, Dodman NH. The use of clonidine in the treatment of fear-based behavior problems in dogs: an open trial. Journal of Veterinary Behavior. 2011; 6( 2): 130 – 137. Available from: https:// doi. org / 10.1016 / j. jveb. 2010.10.004.
26 Gomart SB, Allerton FJW, Gommeren K. Accuracy of different temperature reading techniques and associated stress response in hospitalized dogs. Journal of Veterinary Emergency and Critical Care. 2014; 24( 3): 279 – 285. Available from: https:// doi. org / 10.1111 / vec. 12155.
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