N1033787
These studies are difficult to compare to the current study as their investigations include different species( rats vs dogs), different routes of administration( intramuscular vs intravenous), or asses the drugs used independently( as compared to the premedication combinations investigated in the current study). In the current study, inclusion of premedication as a variable was limited to the drug types used( for example opioids, or α2- adrenergic receptor agonists etc), dosages, time and route of administration was not included. The author believes that the difference in results seen in the current study and those done previously was most likely due to too many variables influencing the results. The investigation into premedication was not specific enough, and numbers were not evenly weighted across the groups. It can be assumed however, from the current study and those done previously, that premedication does influence body temperature, most likely attributed to the sedation, and therefore lack of activity and muscle relaxation that accompanies this, that premedication causes. It is also worth mentioning that the study by Redondo et al( 2012) found that longer times from premedication administration to induction was associated with lower core body temperature post anaesthetic.
5.5 Interpretation of length of MRI procedure affecting body temperature The most obvious finding from the study, and one that is consistent with the findings of several other studies( Shimizu et al, 2022; Clark-Price et al, 2021; Onozawa et al, 2021; Degan et al, 2019; Bruniges and Rioja, 2019; Khenissi et al, 2017) was that the involvement of MRI influenced patient body temperatures, most commonly causing hypothermia. The results of the current study highlighted that the length of time in the MRI suite did affect the patient’ s body temperature, showing that the more minutes they remained in room, the more their body temperature decreased. It is known from human studies that the temperature of the room influences the body temperature of anaesthetised patients and can increase the chances of post-operative hypothermia occurring( Kongsayreepong et al, 2003). MRI room temperatures must remain low so the magnets of the scanner can be kept cool( Khenissi et al, 2017), and in the current study, the room temperature of the MRI suite was on average 20 ° C. The study by Tander et al( 2005) found that a room temperature below 23 ° C is considered relatively cold and interferes significantly with the maintenance of anaesthetised neonatal humans body temperatures. It can therefore be assumed that the necessary cold
ANIM32126 – EBVN Project 30