Plus-Hex CLINICAL
EXCLUSIVE
DIGITAL CONTENT
Answers
1. d) All of the above 2. a) Haematology 3. b) Closed system transfer device 4. c) Somewhere quiet with minimal traffic
REFERENCES
AVAILABLE ONLY IN THE DIGITAL EDITION
Appendix 1a Appendix 1b
Assessment of learning
1. Which items of PPE are essential when preparing a cytarabine CRI?
a) Impermeable gown b) Double chemotherapy-resistant gloves c) Face guard / goggles d) All of the above
2. Which blood test should be run before every cytarabine CRI?
a) Haematology b) Biochemistry c) Electrolytes d) cPL snap test
3. What type of system should ideally be used to prepare a cytarabine CRI?
a) Insulin needle and syringe b) Closed system transfer device c) Luer-lock syringe and needle d) Standard needle and syringe 4. Where should the patient be kennelled? a) In a busy part of the ward b) In complete isolation c) Somewhere quiet with minimal traffic d) In a top kennel
Appendix 2
1 Yale A. Chemotherapy in small animal oncology. Veterinary Ireland Journal. 2021; 11( 9): 530 – 537. Available from: https:// veterinaryirelandjournal. com / small-animal / 264-chemotherapyin-small-animal-oncology [ Accessed 27 May 2025 ].
2 Nind F. Cytotoxic drugs. In: Nind F, Mosedale P.( eds.) BSAVA Guide to the Use of Veterinary Medicines. Gloucester: BSAVA Publications; 2022. p. 18 – 20.
3 Smith AN, Klahn S, Phillips B, Parshley L, Bennett P, Flory A, et al. ACVIM small animal consensus statement on safe use of cytotoxic chemotherapeutics in veterinary practice. Journal of Veterinary Internal Medicine. 2018; 32( 3): 904 – 913. Available from: https:// doi. org / 10.1111 / jvim. 15077.
4 National Institute for Occupational Safety and Health. Personal Protective Equipment for Health Care Workers Who Work with Hazardous Drugs. 2008. Available from: https:// www. cdc. gov / niosh / docs / wp-solutions / 2009-106 / pdfs / 2009-106. pdf [ Accessed 10 December 2022 ].
5 Halyard Health. You’ re Fighting Cancer. Wear the Battle Gear That Protects Against 52 Chemotherapy Drugs! Available from: https:// www. halyardhealth. com / wp-content / uploads / 2020 / 12 / Chemo- Gear-52-Drugs _ Products-Codes-1. pdf [ Accessed 21 December 2022 ].
6 Hague P. EU Declaration of Conformity PPE Critical Environment Gloves. Available from: https:// assets. fishersci. com / TFS-Assets / CCG / EU / Molnlycke / brochures // CE _ 17865738 _ EN. pdf [ Accessed 2 July 2025 ].
7 Santillo M, Field A, Henderson J, Hogan A, Thoms E, Manomano N, et al. Guidance on Handling of Injectable Cytotoxic Drugs in Clinical Areas in NHS Hospitals in the UK. Edition 1. 2018. Available from: https:// www. sps. nhs. uk / wp-content / uploads / 2018 / 07 / Guidance-on-Handling-Cytotoxics-Ed-1-July-2018. pdf [ Accessed 2 July 2025 ].
8 Biller B, Berg J, Garrett L, Ruslander D, Wearing R, Abbott B, et al. 2016 AAHA Oncology Guidelines for dogs and cats. Journal of the American Animal Hospital Association. 2016; 52( 4): 181 – 204. Available from: https:// doi. org / 10.5326 / jaaha-ms-6570.
9 Bisson JL, Argyle DJ, Argyle SA. Antibiotic prophylaxis in veterinary cancer chemotherapy: a review and recommendations. Veterinary and Comparative Oncology. 2018; 16( 3): 301 – 310. Available from: https:// doi. org / 10.1111 / vco. 12406.
10 European College of Veterinary Internal Medicine of Companion Animals. Preventing occupational and environmental exposure to cytotoxic drugs in veterinary medicine. 2007. Available from: https:// chemopet. co. uk / wp-content / uploads / 2021 / 05 / Guidelines-ECVIM- Hazards-Cytotoxic-drugs-2nd-version-July-2007. pdf Accessed 10 December 2022 ].
11 B. Braun Medical Inc. OnGuard ® 2. Available from: https:// www. bbraunusa. com / en / products / b5 / onguard-2. html [ Accessed 27 May 2025 ].
12 MacDonald V. Chemotherapy: managing side effects and safe handling. Canadian Veterinary Journal. 2009; 50( 6): 665 – 668. Available from: https:// pmc. ncbi. nlm. nih. gov / articles / PMC2684058 / [ Accessed 27 May 2025 ].
13 Anon. Safety and handling of chemotherapeutic agents. In: Ramsey I.( ed.) BSAVA Small Animal Formulary Part A: Canine and Feline. 9th ed. Gloucester: BSAVA Publications; 2019. p. 430 – 433.
14 Moore AS, Frimberger AE. Veterinary Oncology Consultants Pty Ltd. Body Surface Area Metre Squared conversion chart: cats. Available from: https:// www. vetoncologyconsults. com / wp-content / uploads / 2022 / 02 / Cat _ BSA _ Chart. pdf [ Accessed 13 January 2023 ].
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