Align-ju SCIENCE SHORTS
Use of maropitant for pain relief in rabbits undergoing neutering procedures
USER-ALT Maya Grayck and others , Colorado State University , Fort Collins , USA
Rabbits may be neutered to prevent breeding or to control conditions affecting the reproductive organs . Either opioids or non-steroidal anti-inflammatory drugs are commonly used to manage postoperative pain in this species , but both drug groups may cause adverse reactions , such as reduced food and water intake and gut stasis . The authors investigated the safety and efficacy of maropitant used for pain control in rabbits . This neurokinin receptor antagonist was originally developed to control motion sickness and vomiting in dogs . It was given subcutaneously at doses of 2 or 4 mg / kg to male and female rabbits before surgical neutering . At the higher dose , rabbits had lower pain scores and resumed feeding sooner . There were no significant differences between the treatment groups in facial grimace scores , total food intake or faecal output .
Topics in Companion Animal Medicine https :// doi . org / 10.1016 / j . tcam . 2024.100888
Effect of hydrocolloid and nitric oxide wound dressings on healing rates
USER-ALT Jenniffer Rodriguez-Diaz and others , University of Georgia , Athens , USA
High standards of wound management may limit the costs incurred through regular wound dressing changes , further surgical intervention , multidrug-resistant infections and prolonged postoperative care . The authors examined the quality of wound healing of four experimental lesions on the trunks of six beagles , which were dressed with either a nitric oxide wound pad , a nitric oxide wound gel , a plain hydrocolloid wound dressing or a Telfa pad . The time to the first appearance of granulation tissue was significantly shorter with the nitric oxide wound pad than with the other dressings . The authors state that nitric oxide wound dressings are innovative and inexpensive products that can significantly decrease the time and cost of achieving open or second-intention wound resolution in dogs .
Veterinary Surgery https :// doi . org / 10.1111 / vsu . 14149
Efficacy of a combination of plant extracts in controlling periodontitis
USER-ALT Se Eun Kim and others , Haemaru Animal Referral Hospital , Seongnam , South Korea
Periodontitis is a common condition in dogs , involving the destruction of tissues supporting the teeth due to a host immune response triggered by plaque . In an experimental model of canine periodontitis , the authors investigated the use of two plant extracts that have been shown to modify the mammalian immune response . Five dogs with ligature-induced disease were given capsules containing 40 mg of Magnoliae cortex extract and 20 mg of Zea mays ( sweetcorn ) extract daily for 2 weeks . Compared with the dogs given a placebo , the treatment group showed a significant reduction in gingival inflammation . Improvements in the periodontal pocket depth , clinical attachment loss and incidence of bleeding were accompanied by reductions in the expression of inflammatory cytokines .
BMC Veterinary Research https :// doi . org / 10.1186 / s12917-024-04243-0
Volume 40 ( 1 ) • February 2025
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